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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LIFR All Species: 23.03
Human Site: Y807 Identified Species: 56.3
UniProt: P42702 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P42702 NP_001121143.1 1097 123743 Y807 D L Q G K T S Y H L V L R A Y
Chimpanzee Pan troglodytes XP_001141959 1097 123652 Y807 D L Q G K T S Y H L V L R A Y
Rhesus Macaque Macaca mulatta XP_001082842 1083 122228 Y793 D L Q G K T S Y H L V L R A Y
Dog Lupus familis XP_546341 967 108830 G697 K Q K M F V V G N L Q P E S F
Cat Felis silvestris
Mouse Mus musculus P42703 1092 122555 Y802 D L Q G K T S Y H L V L R A Y
Rat Rattus norvegicus O70535 1093 122376 Y803 D L Q G K T S Y H L V L R A Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507581 966 108440 V696 G P E K D M Y V V T K E N S I
Chicken Gallus gallus NP_989906 1083 120845 Y788 D L Q G K T S Y Q L D L Q A Y
Frog Xenopus laevis NP_001124412 881 98985 E611 K F A N G E V E A I V V S C C
Zebra Danio Brachydanio rerio NP_001014328 929 102512 S659 V K S L S L S S Y K F I V K A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 95.8 29 N.A. 75.2 74.1 N.A. 61.3 52.2 20.3 26.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.9 97.4 45.5 N.A. 85.5 84.9 N.A. 72.5 70 37.1 43.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 100 100 N.A. 0 80 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 33.3 N.A. 100 100 N.A. 13.3 86.6 20 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 0 10 0 0 0 0 60 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % C
% Asp: 60 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % D
% Glu: 0 0 10 0 0 10 0 10 0 0 0 10 10 0 0 % E
% Phe: 0 10 0 0 10 0 0 0 0 0 10 0 0 0 10 % F
% Gly: 10 0 0 60 10 0 0 10 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 50 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 10 % I
% Lys: 20 10 10 10 60 0 0 0 0 10 10 0 0 10 0 % K
% Leu: 0 60 0 10 0 10 0 0 0 70 0 60 0 0 0 % L
% Met: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 10 0 0 0 10 0 0 % N
% Pro: 0 10 0 0 0 0 0 0 0 0 0 10 0 0 0 % P
% Gln: 0 10 60 0 0 0 0 0 10 0 10 0 10 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 50 0 0 % R
% Ser: 0 0 10 0 10 0 70 10 0 0 0 0 10 20 0 % S
% Thr: 0 0 0 0 0 60 0 0 0 10 0 0 0 0 0 % T
% Val: 10 0 0 0 0 10 20 10 10 0 60 10 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 60 10 0 0 0 0 0 60 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _